Uncovering Conformational Substates and Kinetic Constants by Pressure Modulation
نویسندگان
چکیده
منابع مشابه
Revealing conformational substates of lipidated N-Ras protein by pressure modulation.
Regulation of protein function is often linked to a conformational switch triggered by chemical or physical signals. To evaluate such conformational changes and to elucidate the underlying molecular mechanisms of subsequent protein function, experimental identification of conformational substates and characterization of conformational equilibria are mandatory. We apply pressure modulation in co...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.11.369